Ellegren Lab

Contact Info

Hans Ellegren

hans.ellegren@ebc.uu.se

+46 (0)18-471 6460 (office)
+46 (0)18-471 6310 (fax)

Mailing address:

Dept. of Evolutionary Biology, EBC,
Uppsala University,
Norbyägen 18D,
75236 Uppsala, Sweden

Visiting address:

EBC, Norbyvägen 18D
 

Ellegren Lab

Ellegren Lab

To see the names click on the picture.

Research in my laboratory addresses some key questions in evolutionary biology mainly using genetic and genomic approaches. This includes understanding the genetic basis for post-reproductive isolation during the speciation process, which we study using the collared flycatcher – pied flycatcher model system of speciation. We have recently sequenced and assembled the genome of both species. It also includes, since many years, general molecular evolutionary studies of how mutation, selection and recombination mould DNA sequence evolution. Another line of research deals with characterizing the genetic bias to important fitness-related traits in bird populations. Here, a key approach involves QTL mapping in zebra finch. Finally, we are interested in, also since long, sex chromosome evolution and sex-biased gene expression.

Selected recent publications

  • Corl, A. & Ellegren, H. (2012) The genomic signature of sexual selection in the genetic diversity of the sex chromosomes and autosomes. Evolution, in press.
  • Schielzeth, H., Forstmeier, W., Kempenaers, B. & Ellegren, H. (2012) QTL linkage mapping of wing length in zebra finch using genome-wide SNP markers. Molecular Ecology 21:329-339.
  • Schielzeth, H., Kempenaers, B., Ellegren, H. & Forstmeier, W. (2012) QTL linkage mapping of zebra finch beak colour shows an oligogenic control of a sexually selected trait. Evolution 66:18-30.
  • Ellegren, H. (2011) Emergence of male-biased genes on the chicken Z-chromosome: Contrasts between male and female heterogametic systems. Genome Res 21:2082-2086.
  • Künstner, A., Nabholz, B. & Ellegren, H. (2011) Significant selective constraint at 4-fold degenerate sites in the avian genome and its consequence for detection of positively selected genes. Genome Biol Evol 3:1381-1389
  • Mugal, C.F. & Ellegren, H. (2011) Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content. Genome Biol 12:R58.