Contact Info
Mattias Jakobsson
mattias.jakobsson[at]ebc.uu.se
+46 (0)18-471 6449 (office)
+46 (0)18-471 6310 (fax)
Mailing address:
Dept. of Evolutionary biology, EBC,
Uppsala University,
Norbyägen 18D,
75236 Uppsala, Sweden
Visiting address:
EBC, Norbyvägen 18D, Room 1036
Mattias Jakobsson Lab
News: Feb 15, 2013 -- Mattias Jakobsson received the Tage Erlander Prize from the Royal Swedish Academy of Sciences
News: Sept 20, 2012 -- Our paper on southern Africas Khoe and San populations was published in Science -- see News and Events
News: July 9, 2012 -- An ERC Starting Grant was awarded to Mattias Jakobsson
News: April 26, 2012 -- Our paper on Stone Ages Europeans was published in Science -- see News and Events
Top row, from left: Pontus Skoglund, Mattias Jakobsson, Carina Schlebusch, Per Sjödin, Solenn Stoeckel. Front row, from the left: Helena Malmström (inset) Katie Owers, Lucie Gattepaille, Sen Li. Inset: Agnes Sjöstrand.
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Mattias JakobssonAssistant Professor We are associated with:Department of Evolutionary Biology |
Research interests
The research focuses on understanding evolutionary and demographic processes by using mathematical models and developing and utilizing statistical and computational methods for analyzing large genomic data sets. Specifically, we are interested in:
- Human evolutionary genetics and inferring demographic history based population-genetic data.
- Theoretical population genetics.
- Developing methods for searching for genes targeted by recent selection.
- Models of founder events and their implications for patterns of genetic variation.
- The impact of demography on gene-mapping.
Background
2008- : Assistant Professor, Uppsala University
2005-2008: Postdoc, Computational biology, Rosenberg Lab, University of Michigan.
2005: PhD, Genetics, Section for Evolutionary Genetics, Lund University.
2003-2004: Research visit at the Nordborg Lab, University of Southern California.
2001: MS Biology and Mathematics, Lund University.
Our research is funded by:
Selected publications
- M Jakobsson, MD Edge, & NA Rosenberg. (2013) The relationship between FST and the frequency of the most frequent allele. Genetics, 193: 515-528.
- CM Schlebusch*, P Skoglund*, P Sjödin, LM Gattepaille, D Hernandez, F Jay, S Li, M De Jongh, A Singleton, MGB Blum, H Soodyall, & M Jakobsson. (2012) Genomic variation in seven Khoe-San groups reveals adaptation and complex African history. Science, 338: 374-379.
- P Skoglund, H Malmström, M Raghavan, J Storå, P Hall, E Willerslev, MTP Gilbert, A Götherström & M Jakobsson. (2012) Origins and Genetic Legacy of Neolithic Farmers and Hunter-Gatherers in Europe. Science, 336: 466-469.
- LM Gattepaille & M Jakobsson. (2012) Combining markers into haplotypes can improve population structure inference. Genetics, 190: 159-174.
- P Skoglund & M Jakobsson. (2011) Archaic human ancestry in East Asia. Proceedings of the National Academy of Sciences USA, 108: 18301-18306.
- MGB Blum & M Jakobsson (2011) Deep divergences of human gene trees and models of human origins. Molecular Biology and Evolution. 28: 889-898.
- M Jakobsson*, SW Scholz*, P Scheet*, JR Gibbs, JM VanLiere, H-C Fung, ZA Szpiech, JH Degnan, K Wang, R Guerreiro, JM Bras, JC Schymick, D Hernandez, BJ Traynor, J Simon-Sanchez, Matarin, M., A Britton, J van de Leemput, I Rafferty, M Bucan, HM Cann, JA Hardy, NA Rosenberg, & AB Singleton, (2008) Genotype, haplotype, and copy number variation in worldwide human populations. Nature, 451: 998-1003.
- M Jakobsson & NA Rosenberg (2007) CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure. Bioinformatics, 23: 1801-1806.