Ellegren Lab

Contact Info

Hans Ellegren

hans.ellegren@ebc.uu.se

+46 (0)18-471 6460 (office)
+46 (0)18-471 6310 (fax)

Mailing address:

Dept. of Evolutionary Biology, EBC,
Uppsala University,
Norbyägen 18D,
75236 Uppsala, Sweden

Visiting address:

EBC, Norbyvägen 18D
 

Ellegren Lab

Ellegren Lab

To see the names click on the picture.

Research in my laboratory addresses some key questions in evolutionary biology mainly using genetic and genomic approaches. This includes understanding the genetic basis for post-reproductive isolation during the speciation process, which we study using the collared flycatcher – pied flycatcher model system of speciation. We have recently sequenced and assembled the genome of both species. It also includes, since many years, general molecular evolutionary studies of how mutation, selection and recombination mould DNA sequence evolution. Another line of research deals with characterizing the genetic bias to important fitness-related traits in bird populations. Here, a key approach involves QTL mapping in zebra finch. Finally, we are interested in, also since long, sex chromosome evolution and sex-biased gene expression. For a more detailed description of our projects, please see Research.

Selected recent publications

  • Mugal, C.F., Arndt, P.F. & Ellegren, H. (2013) Twisted signatures of GC-biased gene conversion embedded in an evolutionary stable karyotype. Molecular Biology and Evolution, in press.
  • Mugal, C.F., Nabholz, B. & Ellegren, H. (2013) Genome-wide analysis in chicken reveals that local levels of genetic diversity are mainly governed by the rate of recombination. BMC Genomics 14:86.
  • Adolfsson, S. & Ellegren, H. (2013) Lack of dosage compensation accompanies the arrested stage of sex chromosome evolution in ostriches. Molecular Biology and Evolution 30:806-810.
  • Parsch, J. & Ellegren, H. (2013) The evolutionary consequences of sex-biased gene expression. Nature Reviews Genetics 14:83-87.
  • Backström, N., Saetre, G.P. & Ellegren, H. (2013) Inferring the demographic history of European Ficedula flycatcher populations. BMC Evolutionary Biology 13:2.
  • Ellegren et al. (2012) The genomic landscape of species divergence in Ficedula flycatchers. Nature 491:756-760